Hi Torn, almost a year ago, I was exactly in the same circumstance as you (hence my lovely user name). How long have you two been together? Have you seen any signs of infidelity, including any behavior changes, other than the HPV?
I am a researcher by training (statistics), so I spent a ton of time researching HPV. I read the actual studies rather than relying upon "google research," which is confusing and contradictory. HPV is tricky because there is a small probability that it can come out of remission after a long time, BUT the odds grow smaller as time elapses and you've both been faithful. Many people cling to that tiny hope and decide to believe their spouse. But given you're here, I suspect that you (like I) have seen other signs.
After I was diagnosed with HPV (plus it was CIN 1), and my husband denied any infidelity, I quietly slid into Search mode. Ultimately, I discovered that he was actively pursuing affairs for a long time, but I never did find anything to suggest a PA. The EAs are devastating, but I'm glad I know.
My advice to you is to do the same - quietly search everything - otherwise, 10 years from now, you will still wonder whether he really cheated. It's truly best to know the truth, one way or the other. Search his phone (texts and emails), your phone records (look for calls or texts to one or two numbers), his computer, browser history, everything. There is even software to recover deleted texts, and to track his phone so you know his true whereabouts. Place a VAR (voice activated recorder) in his car and home office. Change your own behavior patterns. I caught my WH by dropping by his office unexpectedly (his current EA was with a coworker).
And if you find anything, DON'T confront him immediately. Post here for more advice, and collect a full range of evidence before you a approach him with it. Otherwise, he is apt to lie (as many do), and it will take a lot longer to find anything once he starts erasing. So it's important to act nonchalant for now, so he's off his guard. I sucked at that, by the way, but it would have been helpful.
Good luck, post often. People here are a fantastic source of support.