You can definitely ask a mod to start a thread re: mood disorders.
I'll reply to you here though just for ease.
My SAXH is not bipolar (most likely borderline, he has not been formally diagnosed but my IC and I have talked about it a lot and have agreed that it is likely). BUT, my younger brother is bipolar 2, and having just been through his first manic episode about 3 years ago, I can tell you watching a loved one go through it is very difficult.
My brother's episode was so bad that he was actually in the psychiatric ICU for 6 weeks before they felt comfortable releasing him. He was HYPER sexual, making all sorts of comments and gestures, although in the controlled setting of the ICU did not have a chance to act on any of those impulses. I can't imagine how hurtful it must be for you to have discovered her As. It must also be really difficult to define what happened due to her chemical imbalances, and what was just due to poor boundaries etc.
I can tell you that watching my brother when he was manic, it was clear to me and everyone around him that he was absolutely not the person we know and love. It was a total mindf*ck because, apart from the lack of hygiene which so many manic people have, for the most part he looked and sounded the same. But his actions and the actual words he was speaking did not line up with who he is as a person.
It took a while to get his meds figured out. But I will say that getting into a very regular routine of working out every morning, going to bed and waking up at very specific times every day, as well as religiously taking his meds, has improved his well being immensely. He is the brother I know and love, only now he is even more self aware and takes care of himself first and foremost.
I've spoken with his psychiatrist and he maintains that my brother was one of the worst cases he's ever seen, tied with only one other patient in his 20 year practice. He also says that he is one of his biggest success stories, and he strongly believes that his workout regimen is a huge factor in that. He also recommends melatonin for sleep, as well as fish oil for cognitive function improvement.
Because my father has now been seeing him and the dr. thinks that he has some bipolar tendencies as well, he has recommended that my other brothers and I also go on fish oils, as these things tend to run in families, and the medications that work for your family members often also work for you too.
Does her family have any history of bipolar? It would be incredibly helpful for you to find out.
Also, in regards to the shame over the behaviors, this is something that she should be addressing in regular therapy. Many of the behaviors my brother engaged in while manic were absolutely ridiculous to any sane person, and he had a hard time even believing that he did them at all, as his memory of the episode was incredibly foggy. Even the things he did remember were very, very skewed from the reality of what was actually happening.
He also had a hard time wanting to stay on the meds for a while, because when he was manic he felt invincible and afterward he said he "missed" the person that he was when he was unmedicated. It took some time for him to come to terms with the fact that most of the "experiences" he remembered from his manic state did not even actually happen, or if they did, the details were far different from what he remembered. He had to go through the stages of grief and mourn that "reality" as something that would never come back.
Anyway, I know how difficult the journey can be when you love someone who is bipolar. I hope your wife goes to therapy to work on her shame. I'm sorry that you probably won't ever know which of the behaviors were just regular old A behaviors, and which were due to the chemical imbalances. Unfortunately, it's next to impossible to figure that out. But hypersexuality is an extremely common symptom amongst bipolars who are in a manic state, so hopefully you, and she, can find some comfort in knowing that she is not alone in that.